CONGENITAL ANOMALIES IN CHILDREN REVALENCE AND RISK FACTORS
Ключевые слова:
congenital anomalies, congenital malformation, congenital heart defects, perinatal causesАннотация
Congenital malformations have been in the focus of physicians since ancient times, but despite their centuries-old history, many aspects of the etiology and pathogenesis of congenital malformations in humans have not been adequately studied even today. Congenital deficiencies of development are defined as stable morphological changes that go beyond the limits of structural variations of members or parts of organs and disrupt their function.Apply the term “sporadic the defect of birth”,meaningunknown cause, accidental appearance and low riskreappearance have future children. For 20-25% of anomalies more likely “multi-factor” reason – complexinteraction many small geneticdefects andrisk factorsenvironmental environment. The rest 10-13% of anomalies associated with the influence environment. Only 12-25% of anomalies have purely genetic causes.
