EVALUATION OF THE FUNCTIONAL STATE OF VASCULAR ENDOTHELIAL CELLS IN PATIENTS WITH REACTIVE DYSTROPHIC DISEASES OF THE SALIVARY GLANDS
Ключевые слова:
salivary glands, reactive dystrophic diseases, sialadenosis, oral fluid, endothelial cells, nitric oxideАннотация
Due the fact that in 70% of cases of admission of patients with diseases of the salivary glands, the correct diagnosis causes significant difficulties, this issue remains an urgent problem of modern medicine. The aim of this study is to study the anticoagulant and fibrinolytic properties of the vascular wall endothelium, as well as to determine the markers of endothelial dysfunction -homocysteine and endothelin in patients with reactive dystrophic diseases of the salivary glands. This article presents the results of a survey of 64 patients with reactive dystrophic diseases (RDD) and inflammatory diseases of the salivary glands (SG) at the age of 20 to 55 years. As a result, it found that, in contrast to healthy individuals, there is an increase in the serum content of not only homocysteine, but also endothelin I. The obtained data allow us to conclude that in patients of this category there are significant violations of the vascular wall thrombosis resistance, which manifested by changes in the anticoagulant and fibrinolytic properties of the endothelium. It also found that in this pathology, there is an increase in the serum content of not only homocysteine, but also endothelin I.
